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The active part of moisture content and, therefore, water activity, provide better information than the total moisture content regarding the micro-biological, chemical and enzymatic stability of perishable products such as foods and seeds. For similar reasons, water activity is equally relevant in the pharmaceutical industry where it provides useful information regarding the cohesion of tablets and pills, or the adherence of coatings. Water activity can be directly compared with the relative humidity of the ambient air to prevent dimensional changes in a product (paper, photographic film), to prevent hygroscopic powders (powdered sugar, salt) from caking or turning into a solid block, etc.
Water activity can be used with some products (mostly synthetic products) as a means of indirectly measuring the total moisture content. This requires developing sorption isotherms to this purpose. Sorption isotherms are graphs that provide the relationship between water activity and moisture content at constant temperature. For most natural products, repeatable sorption isotherms cannot be reliably developed and water activity should be regarded as separate from moisture content.